Falk Gastro Info 7/2016

Video

Video course abdominal ultrasound

Retroperitoneum, lymph node evaluation

Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.

Please switch on your loudspeakers!

Link to Falk Mediacenter

Latest research in brief:

Bowel

Text:

Sandborn WJ et al, N Engl J Med. 2016;374(18):1754–62

Ulcerative colitis: Treatment with the S1P1 receptor agonist ozanimod in a phase 2 trial results in slightly higher remission rates than placebo after 8 weeks.

Link to text

Text:

Perkin MR et al, N Engl J Med. 2016;374(18):1733–43

Food allergies: Randomized trial of early introduction of allergenic foods in breast-fed infants does not show efficacy to reduce the prevalence of food allergies.

Link to text

Text:

Kabbani TA et al, Am J Gastroenterol. 2016;111(5):712–9

Inflammatory bowel disease: Results of a 5-year longitudinal study indicate that vitamin D levels are frequently reduced and associated with higher IBD-related morbidity and disease activity.

Link to text

Liver Biliary Tracts

Text:

Escorsell À et al, Hepatology. 2016;63(6):1957–67

Esophageal variceal bleeding: A current randomized and controlled trial supports the use of an esophageal stent for controlling of acute refractory variceal bleeding: Use of an esophageal stent was superior to balloon tamponade regarding efficacy and severe adverse events.

Link to text

Text:

Foster GR et al, J Hepatol. 2016;64(6):1224–31

Hepatitis C: Direct-acting antivirals are effective in the treatment of patients with hepatitis C and advanced liver disease and lead to an improvement of liver function. Patients with low serum albumin, high age, or low serum sodium concentrations, however, are less likely to benefit from antiviral treatment.

Link to text

Text:

Abraldes JG et al, Gastroenterology. 2016;150(5):1160–70.e3

Esophageal variceal bleeding: Addition of simvastatin to standard therapy (beta-blockers plus band ligation) did not reduce rebleeding but increased overall survival. Due to the risk of rhabdomyolysis, further studies need to confirm these findings prior to their application in clinical practice.

Link to text

Oesophagus Stomach Duodenum

Text:

Lee YC et al, Gastroenterology. 2016;150(5):1113–24.e5

Gastric cancer:Meta-analysis confirms that Helicobacter pylori eradication is associated with reduced tumor incidence.

Link to text

Text:

Krishnamoorthi R et al, Gastrointest Endosc. 2016;83(6):1090–106.e3

Barrett‘s esophagus: Meta-analysis reveals recurrence rates of intestinal metaplasia after successful endoscopic therapy of approx. 10% per year, which emphasizes the need of continuing endoscopic follow-up.

Link to text

Text:

Zingone F et al, Aliment Pharmacol Ther. 2016;44(1):57–67

Celiac disease: Patients under the age of 65 without vaccination against pneumococcus have a markedly increased risk of developing community-acquired pneumonia.

Link to text

Pancreas

Text:

Culver EL et al, Am J Gastroenterol. 2016;111(5):733–43

IgG4-associated autoimmune disease: Only approx. one quarter of patients with elevated IgG4 levels meets the diagnostic criteria of IgG4-related disease. Higher IgG4 concentrations (≥ 2,8 g/l) are useful to confirm the diagnosis and predict multi-organ involvement and risk of relapse.

Link to text

International Symposia and Workshops

Symposium 204

Clinical Hepatology Practice in 2016: From Science to Therapy

September 2 – 3, 2016, Birmingham, United Kingdom

The ICC Birmingham, International Convention Centre, Broad Street, B1 2EA Birmingham, Great Britain

Program

Registration

Online registration

Gastroenterology Symposium

Putting the Puzzle Together: Inflammation and Gastrointestinal Disease

September 16 – 17, 2016, Regensburg, Germany