Video
Video course abdominal ultrasound
Examination of the liver: Portal vein
Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.
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Latest research in brief:
Bowel
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Paramsothy S et al, Lancet. 2017;389(10075):1218–28
Fecal microbiota transplantation (FMT) for ulcerative colitis: Multidonor intensive FMT induces steroid-free clinical remission and endoscopic improvement in approx. 25% of the patients.
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Desai RJ et al, BMJ. 2017;356:j895
Risk of serious infections in pregnant women with autoimmune disease: Risk is similar following treatment with steroids, conventional immunosuppressants and TNF inhibitors, however, high-dose steroid use is an independent risk factor of serious infections during pregnancy.
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Stevens VW et al, JAMA Intern Med. 2017;177(4):546–53
Clostridium difficile infection: Recurrence rates are similar following therapy with metronidazole and vancomycin. However, the risk of 30-day mortality was reduced in vancomycin-treated patients with severe disease.
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Liver Biliary Tracts
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El-Khoueiry AB et al, Lancet. 2017 [Epub ahead of print]
Hepatocellular carcinoma (HCC): In an open-label, non-comperative phase 1/2 study, the checkpoint inhibitor nivolumab demonstrated acceptable tolerability and durable objective response in 15–20% of patients with advanced HCC.
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Seto WK et al, Hepatology. 2017;65(5):1451–61
Hepatitis B virus (HBV): A prospective study demonstrates that 40% of patients with “resolved” hepatitis B (HBsAg-negative, anti-HBc-positive) undergoing allogeneic hematopoietic stem cell transplantation experience HBV reactivation at a median of 44 (8–100) weeks. Age > 50 years and chronic graft versus host disease were associated with HBV reactivation.
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Matsuura K et al, Gastroenterology. 2017;152(6):1383–94
Hepatitis C virus (HCV) and hepatocellular carcinoma (HCC): A single nucleotide polymorphism in the TLL1 gene (tolloid like 1; rs 17047200) is associated with a substantially increased risk for HCC development after successful antiviral therapy for chronic HCV infection.
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Oesophagus Stomach Duodenum
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Thota PN et al, Gastroenterology. 2017;152(5):987–92
Barrett’s esophagus: Risk of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett’s esophagus < 1 cm (irregular Z line) within 5 years of index endoscopy is very low. [x_button type="transparent" shape="pill" size="regular" block="false" circle="false" icon_only="false" href="http://www.drfalkpharma.com/index.php?L=1&id=23927#c33178" title="" target="blank" info="none" info_place="top" info_trigger="hover" info_content=""]Link to text[/x_button] Text: Jensen DM et al, Am J Gastroenterol. 2017;112(3):441–6
Upper gastrointestinal bleeding: Patients with Forrest IB peptic ulcer bleeding (oozing) have a low rebleeding risk within 72 hours irrespective of proton-pump inhibitor therapy with esomeprazole.
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Terheggen G et al, Gut. 2017;66(5):783–93
Neoplastic Barrett’s esophagus: Endoscopic submucosa dissection (ESD) and endoscopic mucosa resection (EMR) are equally effective for endoscopic eradication of early Barrett’s neoplasia. ESD achieves a higher R0 resection rate.
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Pancreas
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Kamal A et al, Am J Gastroenterol. 2017;112(3):503–10
Acute biliary pancreatitis: Approx. 80% of patients underwent cholecystectomy within 30 days. The remaining patients were likely not to be operated and display an elevated risk for subsequent hospitalizations for acute and chronic pancreatitis.
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International Symposia and Workshops
Symposium 208
IX GASTRO-CONFERENCE (Part I)
Eosinophilic Esophagitis – Medical and Dietary Treatment
October 4 – 5, 2017, Berlin, Germany
Maritim Hotel Berlin, Stauffenbergstr. 26, 10785 Berlin, Germany
Registration
Online registration
Symposium 209
IX GASTRO-CONFERENCE (Part II)
IBD 2017 – Therapeutic and Biological Barriers
October 6 – 7, 2017, Berlin, Germany
Maritim Hotel Berlin, Stauffenbergstr. 26, 10785 Berlin, Germany
Registration
Online registration
Current Falk literature:
NEW
Liver function test values
Significance, interpretation, algorithms and peculiarities
Authors: A. Canbay, J. Best, G. Gerken
(35 pages)
U46e
Picture:
http://newsletter.drfalkpharma.de/FGI_6-17/U46e_1-3-17.jpg
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