Falk Gastro Info 6/2016

Video

Video course abdominal ultrasound

Mesenterium, lymph node evaluation

Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.

Please switch on your loudspeakers!

Link to Falk Mediacenter

Latest research in brief:

Bowel

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Erichsen R et al, Gastroenterology. 2016;150(4):895–902.e5

Increased risk of colorectal cancer development among patients with serrated polyps.

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Hassan C et al, Gut. 2016;65(5):806–20

Endoscopic resection of large polyps (≥ 20 mm) is extremely effective and safe. However, adequate endoscopic surveillance is necessary due to relatively high risk of recurrence.

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Baumgart DC et al, Aliment Pharmacol Ther. 2016;43(10):1090–102

Vedolizumab for IBD: German cohort study demonstrates good response rates in patients with Crohn’s disease and ulcerative colitis.

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Liver Biliary Tracts

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Lencioni R et al, J Hepatol. 2016;64(5):1090–8

Hepatocellular carcinoma (HCC): The SPACE study demonstrates that sorafenib plus transarterial chemoembolization with doxorubicin-eluting beads (DEB-TACE) is not superior to DEB-TACE alone.

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Papatheodoridis G et al, Hepatology. 2016;63(5):1481–92

Chronic hepatitis B: A systematic review demonstrates that durable virological remission seems to be feasible in a substantial proportion of patients who discontinue long-term therapy with nucleos(t)ide analogues. On-therapy virological remission > 24 months offers higher chances of off-therapy virological remission in HBeAg-negative hepatitis B.

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Unalp-Arida A et al, Hepatology. 2016;63(4):1170–83

Non-alcoholic fatty liver disease (NAFLD): In the U.S. population, severe hepatic steatosis on ultrasound and elevated liver enzymes (ALT, AST, γGT) are associated with increased liver disease mortality, but are not independently associated with overall mortality.

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Oesophagus Stomach Duodenum

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Gomm W et al, JAMA Neurol. 2016;73(4):410–6

Proton-pump inhibitors are associated with an approx. 1,5-fold increased risk of incident dementia.

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Alexandre L et al, Gastroenterology. 2016;150(4):854–65.e1

Esophageal carcinoma: Statin use after diagnosis of esophageal adenocarcinoma is associated with reduced cancer-specific and all-cause mortality.

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Moonen A et al, Gut. 2016;65(5):732–9

Achalasia: Long-term results of the European achalasia trial indicate that pneumatic dilatation and laparoscopic Heller myotomy are equally effective.

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