Dr. Falk Video report
EoE – State of the Art – PART 3
The most important facts summarized:
- The mean age at diagnosis of EoE in adults is approximately 30 years
- Children are usually diagnosed at the age 6 to 12 years
- Men between 30 and 50 years are affected most frequently
- A delay in diagnosis impacts the quality of life
- A delay in diagnosis can lead to complications, i.e. an increased risk of strictures and stenoses
- Consequently, increased awareness of EoE and an early diagnosis are crucial
Video-Report – PART 3 of the Satellite Symposium „EoE – State of the Art“, which took place during the ueg week 2018 in Vienna (Austria). ). Prof. Dr. Alain Schoepfer from Lausanne (Switzerland) talked about “Delayed diagnosis” of Eosinophilic Esophagitis.
©2019 Dr. Falk Pharma GmbH, Freiburg. All rights reserved.
Please switch on your loudspeakers!
Link to Falk Mediacenter
Latest research in brief:
Bowel
Text:
Ye BD et al, Lancet. 2019;393(10182):1699–707
Biosimilar CT-P13 for Crohn’s disease: Results of a randomized double-blind phase 3 trial confirm that the biosimilar CT-P13 is non-inferior to originator infliximab in patients with active Crohn’s disease in terms of efficacy and tolerability.
Link to text
Text:
Nieuwenburg SAV et al, Gut. 2019;68(5):866–72
Accuracy of fecal immunochemical tests (FITs) in colorectal cancer screening: Meta-analysis confirms that the accuracy of FITs is not affected by concomitant therapies with oral anticoagulants or NSAIDs. Therefore, these medications do not need to be discontinued when performing such tests.
Link to text
Text:
Tian Y et al, BMJ. 2019;364:l803
Familial colorectal cancer risk: Nationwide cohort study reveals that colorectal cancer risk in half-siblings is similar to that in siblings and approx. 1,5- respectively 1,7-fold increased. However, risk among people with one affected second degree relative is negligible.
Link to text
Liver Biliary Tracts
Text:
Woolley AE et al, N Engl J Med. 2019;380(17):1606–17
Hepatitis C virus (HCV): A current study demonstrates that preemptive antiviral treatment prevents HCV infection in HCV-negative patients receiving a heart or lung transplant from HCV-positive donors. Patient and transplant survival remain unaffected. Thus, HCV-positive individuals should no longer be excluded from organ donation.
Link to text
Text:
Villanueva C et al, Lancet. 2019;393(10181):1597–608
Beta-blockers in cirrhosis 1: Long-term treatment with beta-blockers could increase decompensation-free survival in patients with compensated cirrhosis and clinically significant portal hypertension (hepatic venous pressure gradient ≥ 10 mmHg), mainly by reducing the incidence of ascites.
Link to text
Text:
Sharma M et al, Hepatology. 2019;69(4):1657–75
Beta blockers in cirrhosis 2: A current meta-analysis indicates that nonselective beta-blockers may reduce all-cause mortality and the risk of first variceal bleeding in patients with cirrhosis and large esophageal varices. Due to the low complication rate in comparison to variceal band ligation, nonselective beta-blockers may be the preferred initial primary prophylaxis of esophageal variceal bleeding.
Link to text
Oesophagus Stomach Duodenum
Text:
Peerally MF et al, Gastrointest Endosc. 2019;89(4):680–9
Endoscopic therapy of Barrett esophagus after endoscopic resection of high-grade dysplasia: A pilot study suggests that radiofrequency ablation and argon plasma coagulation (APC) have similar efficacy and safety, while APC appears to be more cost effective.
Link to text
Text:
Schnabel L et al, JAMA Intern Med. 2019;179(4):490–8
Health risks following consumption of ultraprocessed food: A large French study reveals that consumption of ultraprocessed foods (including ready-to-eat formulations and food additives) is associated with a low but significantly increased all-cause mortality.
Link to text
Text:
Ibrahim M et al, Gut. 2019;68(5):844–53
Endoscopic therapy of acute variceal bleeding: Early application of hemostatic powder added to standard treatment improved early clinical and endoscopic hemostasis and early survival in a feasibility trial.
Link to text
Pancreas
Text:
Tomoda T et al, Gastroenterology. 2019;156(6):1753–60.e1
Prophylaxis of post-ERCP pancreatitis: Results of a randomized trial involving 886 patients suggest that a combination of sublingual nitrates and rectal Diclofenac is superior to Diclofenac alone and results in an almost 2-fold reduced risk of post-ERCP pancreatitis.
Link to text
International Symposia and Workshops
Symposium 215
IBD: From Diagnosis to Therapy
July 5–6, 2019, St. Petersburg, Russia
Park Inn by Radisson, Pribaltiyskaya, Ul. Korablestroiteley 14, 199226 St. Petersburg, Russia
Registration
Online registration
Current Falk literature:
Eosinophilic Esophagitis (EoE)
Autoren: S. Miehlke, S. Attwood
(44 pages)
JO2e