Falk Gastro Info 12/2015

Video

Video course abdominal ultrasound

Right liver lobe, 3 levels

Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.

Please switch on your loudspeakers!

Link to Falk Mediacenter:

http://media.falkfoundation.de/index.php?id=121&L=1

Link to the video directly:

http://media.drfalkpharma.de/fileadmin/media/06_Liver_Right_liver_lobe_3_levels_ENG.mp4

Preview images:

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Latest research in brief:

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Bowel

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Text:

Böhn L et al, Gastroenterology. 2015;149(6):1399–1407.e2

Dietary approaches for irritable bowel syndrome: A diet low in FODMAP reduces symptoms as well as traditional dietary advice (regular meal pattern, avoidance of fat, insoluble fibers, caffeine, and gas-producing foods).

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#30591

Text:

Khanna R et al, Lancet. 2015;386(10006):1825–34

Therapy algorithms for Crohn’s disease: Early combined immunosuppression (antimetabolite plus TNF antagonist) is not superior to conventional therapy in controlling disease activity, but results in reduced rates of disease-related complications including operations and hospital admissions.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30592

Text:

Baron JA et al, N Engl J Med. 2015;373(16):1519–30

Prevention of colorectal adenomas: Daily supplementation of vitamin D3 (1000 IU), calcium (1200 mg) or both after removal of adenomas does not reduce the risk of recurrent colorectal adenomas over a period of 3–5 years.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30593

Liver
Biliary Tracts

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Text:

Roth D et al, Lancet. 2015;386(10003):1537–45

Hepatitis C: In patients with chronic kidney disease stage 4–5 (including patients on hemodialysis) and hepatitis C virus genotype 1, once daily grazoprevir plus elbasvir is well tolerated and highly efficient (sustained virological response rate 99%).

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30594

Text:

van Meer S et al, J Hepatol. 2015;63(5):1156–63

Hepatocellular carcinoma (HCC): The benefit of surveillance for HCC is controversial. A Dutch study now demonstrated that surveillance for HCC is associated with smaller tumor size and earlier tumor stage at HCC diagnosis, impacts therapeutic strategy and is an independent predictor of survival.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30595

Text:

Kirstein MM et al, Hepatology. 2015;62(5):1524–35

Autoimmune hepatitis: Diagnosis at an age < 18 years, histological presence of cirrhosis at diagnosis, and detection of SLA/LP antibodies are main risk factors for a poor short and long-term outcome of autoimmune hepatitis. Positivity for DRB1-04:01, in contrast, is associated with a favorable clinical course.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30596

Oesophagus

Stomach

Duodenum

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Text:

Moawad FJ et al, Gut. 2015;64(12):1874–80

Barrett’s esophagus length is established at the time of initial endoscopy and does not change over time.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30597

Text:

Choung RS et al, Clin Gastroenterol Hepatol. 2015;13(11):1937–43

Symptoms indicative of functional gastrointestinal disorders and seropositive celiac disease are relatively common in a U.S. white community. However, testing for celiac disease in patients with irritable bowel syndrome may not result in improved detection of patients with celiac disease.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30598

Text:

Zeng M et al, Lancet. 2015;386(10002):1457–64

Vaccination against Helicobacter pylori: An oral recombinant vaccine was effective and safe in a randomized placebo-controlled phase III trial of previously uninfected children and resulted in immunogenic responses in 71,8% of study participants.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30599

Pancreas

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Text:

da Costa DW et al, Lancet. 2015;386(10000):1261–8

Biliary pancreatitis: Compared with interval cholecystectomy, same-admission cholecystectomy reduces the rate of recurrent biliary complications with a very low risk of surgery-associated complications.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20376#c30600

Falk Symposia

Workshop

Communications and System Relevance in Liver Damage and Regeneration

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January 21 – 22, 2016, Düsseldorf, Germany

Building 23.01, Hörsaal 3D, Heinrich-Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany

Link1:

http://www.drfalkpharma.com/fileadmin/media/Falk_Veranstaltungen/Falk_Symposien_und_Workshops/WS_Duesseldorf_2016_Preliminary_Program.pdf