Falk Gastro Info 1/2017

Video

Video course abdominal ultrasound

Examination of the mediastinum: Subcarinal region

Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.

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Link to Falk Mediacenter

Latest research in brief:

Bowel

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Mima K et al, Gut. 2016;65(12):1973–80

Microbiota in colorectal carcinoma: The amount of fusobacterial DNA in tumor samples correlates with shorter patient survival.

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Feagan BG et al, N Engl J Med. 2016;375(20):1946–60

Ustekinumab in Crohn’s disease: Phase 3 trial program demonstrates efficacy in induction and maintenance therapy.

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Watanabe T et al, Gastroenterology. 2016;151(6):1122–30

Surveillance colonoscopy of ulcerative colitis patients: Targeted and random biopsies yield similar proportions of dysplasia, whereas targeted biopsies appear to be more cost-effective.

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Liver Biliary Tracts

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Knop V et al, J Viral Hepat. 2016;23(12):994–1002

Hepatitis C: Interferon-free antiviral treatment leads to a reduction of liver stiffness. This effect is more pronounced during antiviral therapy than after end of therapy, suggesting that the reduction of liver stiffness is mostly due to reduced necroinflammation and to a lesser extend to regression of cirrhosis.

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Zenouzi R et al, Clin Gastroenterol Hepatol. 2016;14(12):1806–12

Primary sclerosing cholangitis (PSC): According to a recent retrospective analysis, azathioprine therapy in patients with associated inflammatory bowel disease or overlap with autoimmune hepatitis does not increase the risk for cholangiocellular carcinoma.

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Mittal S et al, J Hepatol. 2016;65(6):1148–54

Hepatocellular carcinoma (HCC): HCC surveillance is associated with a 38% reduction in overall mortality. This reduction in mortality risk is mediated by diagnosis of early HCC stages and receipt of HCC-specific treatment.

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Oesophagus Stomach Duodenum

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Othman F et al, BMJ. 2016;355:i5813

Community-acquired pneumonia (CAP) before and after proton-pump inhibitor (PPI) prescription: Although PPI use increases the risk of CAP, this is likely due to confounding factors such comorbidities.

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Ray WA et al, Gastroenterology. 2016;151(6):1105–12.e10

Risk of upper gastrointestinal bleeding in warfarin-treated patients: Proton-pump inhibitor therapy is associated with reduced risk of bleeding, in particular in patients also taking antiplatelet drugs or non-steroidal anti-inflammatory drugs.

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Liou JM et al, Lancet. 2016;388(10058):2355–65

Helicobacter pylori: Bismuth-containing quadruple therapy for 10 days as first line eradication therapy is superior to triple therapy for 14 days.

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Pancreas

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Tol JAMG et al, Gut. 2016;65(12):1981–7

Preoperative billiary drainage in patients with pancreatic cancer: Although early surgery remains standard of care, fully covered self-expandable metal stents are superior to plastic stents with regard to procedure-related complications.

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International Symposia and Workshops

Workshop

Future Perspectives in Hepatology: From Basics to Clinics

January, 19 – 20, 2017, Essen, Germany

Universitätsklinikum Essen, Audimax, Hufelandstr. 55, 45147 Essen, Germany

Program

Registration

online registration

Symposium 206

From the New and Complex Concepts to the Real Patient: Science and Clinic in IBD

March 31 – April 1, 2017, Madrid, Spain