Video course abdominal ultrasound
Examination of the abdominal vessels – Celiac trunk, Doppler techniques
Author: Prof. Dr. Christoph F. Dietrich ©2019 Falk Foundation e.V., Freiburg. All rights reserved.
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Latest research in brief:
Bowel
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Sandborn WJ et al, N Engl J Med. 2021;385(14):1280–91
Ozanimod for ulcerative colitis: The sphingosine-1-phosphate receptor modulator Ozanimod was more effective than placebo as induction and maintenance therapy in patients with moderately to severely active ulcerative colitis.
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Fleischmann C et al, Gastroenterology. 2021;161(4):1168–78
Endoscopic submucosal dissection (ESD) in Germany: ESD achieved excellent en bloc resection rates but only modest curative resection rates in a German prospective ESD registry comprising 1000 lesions. Moreover, the results varied significantly depending on the center’s yearly case volume.
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Lu TX et al, Gut. 2021;70(11):2076–84
Influence of proton-pump inhibitor (PPI) therapy on the outcome of infliximab therapy in inflammatory bowel disease (IBD): This patient-level meta-analysis of randomized controlled trials indicates that IBD patients taking PPI are less likely to achieve remission.
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Liver Biliary Tracts
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Sanyal AJ et al, N Engl J Med. 2021;385(17):1559–69
Non-alcoholic fatty liver disease (NAFLD): A current prospective study demonstrates the important impact of fibrosis stage on prognosis of NAFLD: Fibrosis stages F3 and F4 are associated with increased risks of liver-related complications (variceal hemorrhage, ascites, encephalopathy, or hepatocellular carcinoma) and death.
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Arab JP et al, J Hepatol. 2021;75(5):1026–33
Steroids in alcohol-associated hepatitis (PRO): A recent retrospective, international, multicenter cohort study shows that steroids improve 30-day survival in patients with severe alcohol-associated hepatitis, especially those with a MELD score (model for end-stage liver disease) between 25 and 39.
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Otero Sanchez L et al, Hepatology. 2021;74(5):2714–24
Steroids in alcohol-associated hepatitis (CONTRA): A current observational study shows that both, patients with severe alcohol-associated hepatitis as well as patients with decompensated alcohol-associated cirrhosis are very susceptible to infection. Patients with severe alcohol-associated hepatitis or a high MELD score (model for end-stage liver disease) have a particularly high risk. However, the main risk factor for invasive fungal infection is steroid treatment, not severe alcohol-associated hepatitis itself.
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Oesophagus Stomach Duodenum
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Seo SI et al, Gut. 2021;70(11):2066–75
Association between proton-pump inhibitor (PPI) use and gastric cancer: Analysis of a population-based cohort study from Korea suggest that PPI use is associated with an approx. 2,37-fold increased risk of subsequent gastric cancer. These findings were irrespective of Helicobacter pylori eradication status.
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Merino J et al, Gut. 2021;70(11):2096–104
Diet quality and risk and severity of COVID-19: A diet characterized by plant-based foods was associated with lower risk and severity of COVID-19. This association may be particularly evident in patients living in areas with higher socioeconomic deprivation.
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Jensen DM et al, Clin Gastroenterol Hepatol. 2021;19(11):2315–23.e2
Over-the-scope clips (OTSC) as initial treatment of severe non-variceal upper gastrointestinal bleeding: In a small randomized trial with 53 patients, OTSC significantly reduced rates of rebleeding, severe complications and transfusions as compared to conventional endoscopic hemostasis.
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Pancreas
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Seo SI et al, Gut. 2021;70(11):2066–75
Association between proton-pump inhibitor (PPI) use and gastric cancer: Analysis of a population-based cohort study from Korea suggest that PPI use is associated with an approx. 2,37-fold increased risk of subsequent gastric cancer. These findings were irrespective of Helicobacter pylori eradication status.
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Symposia 227
Pathophysiology and Clinical Management of Alcoholic Liver Disease
January 27 – 28, 2022, Mannheim, Germany
Barockschloss Mannheim, Room SO 108, Bismarckstraße, Schloss Mittelbau, 68161 Mannheim, Germany
Program
Online registration
Current Falk literature:
No literature.