Falk Gastro Info 11/2015

Video

Video course abdominal ultrasound

Left liver lobe: Segmental anatomy

Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.

Please switch on your loudspeakers!

Link to Falk Mediacenter:

http://media.falkfoundation.de/index.php?id=120&L=1

Link to the video directly:

http://media.drfalkpharma.de/fileadmin/media/05_Liver_Left_liver_lobe_Segmental_anatomy_ENG.mp4

Preview images:

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Latest research in brief:

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Bowel

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Text:

Lang A et al, Clin Gastroenterol Hepatol. 2015;13(8):1444–9.e1

Clinical trial for ulcerative colitis: Addition of curcumin to mesalazine therapy was superior to the combination of placebo and mesalazine in inducing clinical and endoscopic remission in patients with mild-to-moderate active ulcerative colitis, producing no apparent adverse effects.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#29576

Text:

Leifeld L et al, Clin Gastroenterol Hepatol. 2015;13(10):1776–81

Surveillance colonoscopy for ulcerative colitis: Combining targeted and segmental biopsies and narrow band imaging is as sensitive as multiple stepwise biopsies in white endoscopy to identify dysplastic lesions, but requires significantly fewer biopsy specimens and less time.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29577

Text:

Salminen P et al, JAMA. 2015;313(23):2340–8

Antibiotic treatment versus surgery for uncomplicated appendicitis: Most patients with antibiotic treatment did not require appendectomy during a 1-year follow-up period, and those who required appendectomy did not experience significant complications.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29578

Liver
Biliary Tracts

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Chen HL et al, Hepatology. 2015;62(2):375–86

Hepatitis B: Treatment with tenofovir from 30-32 weeks of gestation for highly viremic mothers decreases the mother-to-infant transmission of hepatitis B virus. In a prospective, controlled study, the transmission rate decreased from 10.7% without antiviral medication to 1.5% with tenofovir.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29579

Text:

Cavallin M et al, Hepatology. 2015;62(2):567–74

Liver cirrhosis: Treatment strategies for hepatorenal syndrome include terlipressin plus albumin and, especially in countries such as the US where terlipressin is not available, midodrine and octreotide plus albumin. In a randomized, controlled study, terlipressin plus albumin was significantly more effective than midodrine and octreotide plus albumin in improving renal function in patients with HRS.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29580

Text:

Toso C et al, Hepatology. 2015;62(1):158–65

Hepatocellular carcinoma (HCC): Patients with a tumor volume = 115 cm3 and AFP level = 400 ng/ml display low tumor recurrence rates and high survival rates after liver transplantation, even when they are beyond the Milano criteria. Using these expanded inclusion criteria, more HCC patients could profit from liver transplantation.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29581

Oesophagus

Stomach

Duodenum

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Text:

Jairath V et al, Lancet. 2015;386(9989):137–44

Transfusion strategies for gastrointestinal bleeding: A pilot feasibility trial revealed no significant differences in clinical outcomes following restrictive (hemoglobin < 8 g/dl) versus permissive (hemoglobin < 10 g/dl) transfusion policies.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29582

Text:

Li BZ et al, BMJ. 2015;351:h4052

Helicobacter pylori eradication: Comparison of different eradication regimens indicates that concomitant treatments, 10 or 14 days of probiotic supplemented triple treatment, 10 or 14 days of levofloxacin-based triple treatment, 14 days of hybrid treatment, and 10 or 14 days of sequential treatment might all be better alternatives for the eradication of H. pylori than conventional triple therapy.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29583

Text:

Song H et al, BMJ. 2015;351:h3867

Gastric cancer risk: Among patients who undergo gastroscopy with biopsy for clinical indications, approximately 1 in 256 with normal mucosa, 1 in 85 with gastritis, 1 in 50 with atrophic gastritis, 1 in 39 with intestinal metaplasia, and 1 in 19 with dysplasia will develop gastric cancer within 20 years

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29584

Pancreas

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Text:

Buijs J et al, Pancreas. 2015;44(7):1065–71

Prognosis of autoimmune pancreatitis: Despite an excellent initial treatment response, almost half of the patients require maintenance therapy. Pancreatic insufficiency is highly prevalent, which calls for active screening.

Link:

http://www.drfalkpharma.com/index.php?L=1&id=20377#c29585

Falk Symposia

Falk Workshop

Workshop on Gastrointestinal GVHD

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November 13 – 14, 2015, Regensburg, Germany

University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany

Link1:

http://www.drfalkpharma.com/fileadmin/media/Falk_Veranstaltungen/Falk_Symposien_und_Workshops/WS_Regensburg_2015_Program.pdf