Falk Gastro Info 10/2026

Video

New Episode of “One Expert – One Minute”

We are pleased to announce Episode 11 of our “One Expert – One Minute” series. This episode was recorded at the Falk Symposium “Gastrointestinal Inflammation and Neoplasia” in Warsaw.

In Episode 11, Prof. Ana Gutiérrez-Casbas (Alicante) discusses the importance of monitoring in inflammatory bowel diseases (IBD). She emphasizes the value of combining different monitoring tools, including intestinal ultrasound and fecal calprotectin, to optimize patient management both at diagnosis and throughout the long-term course of the disease.

Watch Episode 11 with Prof. Ana Gutiérrez-Casbas on “Monitoring in IBD” now:

Link to Falk Mediacenter

In “One Expert – One Minute,” leading researchers share short, concise expert statements that deliver key insights and current perspectives on important topics in gastroenterology and hepatology — clear, focused, and to the point.

Stay tuned for more inspiring one-minute insights from international experts — more episodes will follow soon!

Link to the series

One Expert – One Minute

Episode 11

Prof. Ana Gutiérrez-Casbas, Alicante: Monitoring in IBD

Link to YouTube video directly

Science Movie Warsaw

Long-term medical therapy or early surgical intervention?

In this lecture, three doctors, E. Tulewicz-Marti, F. Rieder and W. A. Bemelman, are discussing evolving perspectives in inflammatory bowel disease management and the multidisciplinary collaboration shaping its future.

Symposium 243, “Gastrointestinal Inflammation and Neoplasia,” held in Warsaw, Poland, in April 2026.

Link to Falk Mediacenter
Link YouTube video directly
Latest research in brief:
Image
Colon to Rectum
Text:

Gharahdaghi N et al, N Engl J Med. 2026;394(22):2212-2222

IL-10 autoantibodies in inflammatory bowel disease: Neutralizing IL-10 autoantibodies were present in a small subgroup (3,5%) of patients with IBD and were strongly associated with HLA-DRB1*01:03, the strongest genetic risk factor of ulcerative colitis.

Link to Falk Mediacenter

Bando H et al, Nat Med. 2026;32(7):2473-2480

Post-adjuvant chemotherapy in circulating tumor DNA (ctDNA)-positive patients with resected colorectal cancer: post-adjuvant chemotherapy did not result in significant longer disease-free survival as compared to placebo in this prospective phase III trial (ALTAIR) in ctDNA-positive patients without radiological disease.

Link to Falk Mediacenter
Image
Liver and Bile Ducts
Text:

Verma M et al, JAMA Intern Med. 2026;186(6):677-686

Palliative care in end-stage liver disease – Hepatologist-led care achieves comparable outcomes: This cluster-randomized trial across 19 US centers included 935 patients with decompensated cirrhosis or hepatocellular carcinoma and compared 4 structured palliative care visits delivered by trained hepatologists with specialist palliative care. Quality of life improved at 3 months in both groups, with hepatologist-delivered care being noninferior to specialist palliative care; symptom burden and depression also improved similarly. The findings demonstrate that, with appropriate training, palliative care can be effectively integrated into hepatology practice.

Link to Falk Mediacenter
Text:

Dongelmans E et al, J Hepatol. 2026;85(1):61-70

Stopping nucleos(t)ide analogues in chronic hepatitis B – Long-term outcomes from the RETRACT-B cohort: The international RETRACT-B cohort evaluated long-term outcomes after nucleos(t)ide analogue treatment cessation in patients with chronic hepatitis B. During long-term follow-up, a small proportion of patients achieved HBsAg loss, while virological and clinical relapses requiring retreatment remained frequent. These findings suggest that carefully monitored treatment cessation may be an option in selected patients with low HBsAg titers but requires close and long-term follow-up.

Link to Falk Mediacenter
Image
Esophagus to Small Intestine
Text:

Leijonmarck W et al, Gastroenterology. 2026;171(3):481-488

Achalasia and esophageal cancer risk: Achalasia was strongly associated with esophageal squamous cell carcinoma in a nordic population-based study. The association with esophageal adenocarcinoma was less strong and largely explained by gastroesophageal reflux.

Link to Falk Mediacenter
Text:

Forbes N et al, Gastroenterology. 2026;171(2):342-353

Cardiovascular outcomes following gastrointestinal bleeding: patients with pre-existing cardiovascular disease and major gastrointestinal bleeding in a large prospective multicenter study (INTERBLEED) had an increased risk to die which was determined by delayed resumption of antithrombotic therapies.

Link to Falk Mediacenter
Image
Pancreas
Text:

Walter T et al, Lancet. 2026;408(10551):234-247

Peptide receptor radionuclide ([177Lu]Lu-edotreotide) vs. everolimus for gastroenteropancreatic neuroendocrine tumours (GEP): [177Lu]Lu-edotreotide led to statistically significant and clinically meaningful improvements in progression-free survival in a randomized phase III trial (COMPETE). Efficacy and harms results support the use of [177Lu]Lu-edotreotide in early lines of therapy in patients with advanced, progressive GEP neuroendocrine tumors.

Link to Falk Mediacenter

Events

Symposium

Symposium: Liver Crosstalk – Immunity, Metabolism, and Tumor Biology

January 28 – 29, 2027, Tübingen, Germany

Kino Museum Tübingen, Am Stadtgraben 2, 72070 Tübingen, Germany

Program
Registration

Symposium 246

Metabolic Syndrome and Liver Disease

March 12 – 13, 2027, Valencia, Spain

Palacio de Congresos de Valencia, Avenida de las Cortes Valencianas 60, 46015 Valencia, Spain

Program
Registration

Symposium 247

Experimental Hepatology Days

May 13 – 15, 2027, Freiburg, Germany

Konzerthaus Freiburg, Konrad-Adenauer Platz 1, 79098 Freiburg, Germany

Program
Registration

Current Falk literature:

Inflammatory Bowel Diseases

Radiological Diagnostics

Author: M. Juchems

(51 pages)