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Video course abdominal ultrasound
Examination of the Liver: Liver surface, examination with high frequency transducer
Author: Prof. Dr. Christoph F. Dietrich, Caritas Krankenhaus Bad Mergentheim.
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Latest research in brief:
Bowel
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Kao D et al, JAMA. 2017;318(20):1985-93
Fecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection: FMT via oral capsules was not inferior to delivery by colonoscopy in a randomized trial.
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Domènech E et al, Inflamm Bowel Dis. 2017;23(10):1840-6
Incidence and management of postoperative recurrence of Crohn’s disease: Spanish “real-life” study indicates that up to one third of patients do not receive preventive medical therapy following ileocecal resection and that almost half of the patients were not endoscopically monitored as recommended.
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Dubé C et al, Am J Gastroenterol. 2017;112(12):1790-801
Risk of advanced adenoma (AA) and colorectal cancer (CRC) in people with low-risk adenomas (LRA) at baseline colonoscopy: There is a small but significantly increased risk of AA in people with LRA compared to people with normal baseline colonoscopy. However, compared to the general population, people with LRA have significantly lower risks of CRC and CRC-related mortality.
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Liver Biliary Tracts
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Yip TCF et al, J Hepatol. 2018;68(1):63-72
Chronic hepatitis B: According to a recent study, nucleos(t)id analogue-induced hepatitis B surface antigen (HBsAg) seroclearance is as durable as spontaneous HBsAg seroclearance. A positive hepatitis B surface antibody (anti-HBs) is not required before stopping treatment, however, an antiviral consolidation treatment for at least 12 months may result in more durable HBsAg seroclearance.
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Torres HA et al, Hepatology. 2018;67(1):36-47
Hepatitis C virus (HCV) and cancer treatment: HCV reactivation is common in patients receiving rituximab or high-dose steroids, however, most patients experience no clinical problems. Thus, HCV infection is no contraindication for cancer treatment. Patients receiving rituximab or high-dose steroids should be monitored closely.
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Kim GA et al, J Hepatol. 2018;68(1):140-6
Non-alcoholic fatty liver disease (NAFLD): NAFLD is associated with development of hepatocellular carcinoma, colorectal cancer in males and breast cancer in females. Risk predictors are high values in the NAFLD fibrosis score and the fibrosis-4 score.
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Oesophagus Stomach Duodenum
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Katzka DA et al, Am J Gastroenterol. 2017;112(10):1538-44
Monitoring of disease activity in eosinophilic esophagitis (EoE): Comparative trial with endoscopy demonstrates that the cytosponge system, is a minimally invasive, safe, well tolerated and accurate method to assess EoE histologic activity.
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Kang YK et al, Lancet. 2017;390(10111):2461-71
Immune therapy for advanced gastric or gastroesophageal junction cancer: The PD-1 antibody Nivolumab results in significant survival benefits in patients after failure or intolerance of 2 lines of standard chemotherapy.
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Bomme M et al, Clin Gastroenterol Hepatol. 2017;15(11):1715-23.e7
Effects of community screening for Helicobacter pylori in a low-prevalence area: Randomized trial with 13 years of follow-up showed no significant effect of screening/eradication of H. pylori on the prevalence of dyspeptic symptoms, incidence of ulcer disease and quality of life, as compared to usual care.
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Pancreas
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van Brunschot S et al, Lancet. 2018;391(10115):51-8
Endoscopic or surgical step-up approach for infected necrotizing pancreatitis: Endoscopic therapy is not superior to surgery in reducing major complications or death. However, the rate of pancreatic fistulas and length of hospital stay were lower in the endoscopy group.
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International Symposia and Workshops
Symposium 210
Crossing New Borders in IBD: Thoughts and Demands – From Mechanisms to Treatment
April 20 – 21, Lisbon, Portugal
Estoril Centro de Congressos, Avenida Amaral, 2765-192 Estoril, Portugal
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Symposium 211
XXV International Bile Acid Meeting: Bile Acids in Health and Disease 2018
July 6-7, 2018, Dublin, Ireland
Clayton Hotel Burlington Road, Upper Leeson Street, D04 A318 Dublin 4, Ireland
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Current Falk literature:
Azathioprine in daily practice
The basic principle of immunosuppressive therapy
Guidance for practical use in gastroenterology and hepatology
Author: J. Weismüller
(41 pages)
Az8e